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High Shear Mixer Granulator

The Hywell Machinery high shear mixer granulator, also called high-speed granulator, rapid mixer granulator, or high shear granulator. High-shear mixer granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper. Dense granules are formed through the liquid and solid bridges that result. For optimal handling and further processing of a product. The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.

  • GHL

  • HYWELL

  • 8479899990

  • SUS304/SUS316L/Titanium

  • Food/Pharmaceutical/Chemical

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High Shear Mixer Granulator Introduction

GHL Series high shear mixer granulator(lab scale)is equipped with a closed container with blending tools driven from above or below, The granulation liquid was poured into the product.

The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.

The wet materials from the high shear mixer granulator and send into the laboratory swaying granulator machine to get 1.5-5mm wet granules, the wet granules can be dried by the laboratory hot air drying oven or lab fluid bed dryer. The final step of the processing system is the granules sifter. The granules sifter will separate the large powder particles from the powder, size is determined for the separation.

Hywell Machinery also has industrial high shear granulator from 50 liters to max 1000 liters if high volume granulator are required.


High Shear Mixer Granulator Description

Hywell Machinery Laboratory model high shear mixer granulator consists of two electric motors, one reduction gear, coupling, and shafts with the two agitators. The shaft is sealed with special sealing, sometimes with an air purge, in a way that there is limited contact between the material and the seal. Materials are loaded from the top side, and the discharge is located at the bottom side.

GHL Series high shear mixer granulators(lab scale super mixing granulator) are equipped with a closed container wih blending tools driven from above or below, The granulation liquid was poured into the product.

The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.


High Shear Mixer Granulator (Lab Model) Working Video



Lab Model High Shear Mixer Granulator Interchangeable Pan

For the lab high shear mixer granulator sizes GHL-1 to GHL-20L, Hywell Machinery offers the option for the lab wet granulation to work with an interchangeable pan. A set main machine is designed to work the materials pan with fast assembly.

Moreover, drums of different sizes can be fit into the same main machine with the necessary adaptor; for example, the GHL series lab high shear mixer granulator can work with drum sizes of 1L up to 10L, and 10-20L by one main machine.

For example, one lab wants to work as 1L, but sometimes, it needs to work as 5L or 10L. so it can buy one set of GHL-10L high shear mixer granulators, and buy one set of 1L materials tank and one set of 5L materials tank as interchangeable.


Lab Scale High Shear Mixer Granulator Change Pan Video


Lab High Shear Mixer Granulators Specifications

Model

Total volume (L)

Operation Volume(L)

Impeller power (Kw)

Impeller speed (rpm)

Chopper power

(kw)

Chopper speed (rpm)

Weight

(Kg)

GHL-5

5

3

2.2

200-450

1.1

1500-2800

120

GHL-10

10

6

2.2

200-450

1.1

1500-2800

130

GHL-20

12

40

2.2

200-450

1.1

1500-2800

160

1.3-10L and 10-20L can work with interchangeable tank.

2.Hywell machinery reserves the right to the design without notice

3.All specifications are as accurate as is reasonably possible, but they are not binding.

4. if you need the bigger model, please see the industrial high shear granulator.


High Shear Mixer Granulation Application

The GHL series lab high shear mixer granulation is widely used in pharmaceutical, chemical, foodstuff, and electronic industries.

1. Pharmaceutical Industry

In the pharmaceutical industry, high-shear granulators are used to produce granules for tablets, capsules, and other dosage forms. They are suitable for processing heat-sensitive and moisture-sensitive drugs and can produce granules with controlled release properties.

2. Chemical Industry

In the chemical industry, rapid mixer granulators are used to produce homogeneous mixtures of powders for various applications. They can also be used to coat particles with a uniform layer of material.

3. Food Industry

In the food industry, high-shear mixer granulators are used to produce granules for instant drinks, seasonings, and other food products. They are suitable for processing heat-sensitive and shear-sensitive ingredients and can produce granules with improved flow properties.


High Shear Mixer Granulator (Lab Scale) Advantages

Hywell machinery laboratory high shear mixer granulator had the following advantages over conventional solutions.

Efficient Granulation Process

High shear mixer granulators are highly efficient when it comes to granulation. They are designed to produce uniform and consistent granules in a short amount of time. This is because the impeller generates a high shear force that promotes the formation of agglomerates, which are then broken down by the chopper. As a result, the granulation process is completed quickly and efficiently.

Homogeneous Granules

One of the primary advantages of high-shear mixer granulators is that they produce homogeneous granules. The impeller and chopper work together to ensure that the powders and liquids are evenly distributed throughout the mixture. This results in granules that have a uniform composition and density.

Consistent Particle Size Distribution

High shear mixer granulators are also capable of producing granules with a consistent particle size distribution. The impeller and chopper work together to break down any lumps and ensure that the granules are of the same size. This is important for applications that require a specific particle size distribution.

High Productivity and Reduced Processing Time

High shear mixer granulators are designed to be highly productive. They are capable of producing large quantities of granules in a short amount of time. This is because the granulation process is completed quickly and efficiently, which reduces processing time and increases productivity.

Improved Powder Flowability

Powder flowability is a critical factor in many manufacturing processes. High shear mixer granulators are capable of improving powder flowability by breaking down any lumps and ensuring a uniform particle size distribution. This results in powders that are easier to handle and transport

Easy Scale-up and Down

High-shear mixer granulators are also designed to be easily scalable. This means that they can be used for both small-scale and large-scale manufacturing processes. The kinds rapid mixer granulator can be easily adjusted to meet the specific needs of each manufacturing process, making it a flexible and versatile tool.

GMP Compliance and Validation

High-shear mixer granulators are designed to meet Good Manufacturing Practice (GMP) standards. This means that they are manufactured to the highest quality standards and are suitable for use in pharmaceutical manufacturing. They are also easy to validate, which is critical in regulatory environments.


What Are High shear mixer granulator?

High-shear mixer granulators are machines used in the pharmaceutical, chemical, and food industries to create homogeneous mixtures of powders or granules. They are specifically designed to process fine powders into granules, improve the flow characteristics of materials, and increase their density.


Types of High shear mixer granulators

High-shear mixer granulators come in different types, including:

1. Vertical High shear mixer granulator

The vertical high shear mixer granulator consists of a vertical cylindrical vessel with a bottom drive unit and a high-speed rotor-stator system. They are suitable for processing powders that require gentle mixing, and they produce uniform and high-quality granules.

2. Horizontal High shear mixer granulator

The horizontal high shear mixer granulator features a horizontal cylindrical vessel with a bottom drive unit and a high-speed chopper impeller. They are suitable for processing powders that require intense mixing, and they produce dense and uniform granules.

3. Laboratory High shear mixer granulator

Laboratory high shear mixer granulators are compact machines designed for small-scale granulation. They are suitable for research and development, and they produce granules with the same quality as larger-scale machines. Hywell Machinery has a lab scale high shear granulator that from 3-20L, and also it can be interchanged pan.


Working Step of High shear mixer granulator

High shear mixer granulator work on the principle of mechanical agitation. They use a combination of shear, compression, and impact forces to mix and granulate powders. The process involves three main stages:

1. Wetting

The first stage involves adding the binder solution to the powder mixture, which creates a wet mass. The wet mass should have a consistent moisture content to achieve optimal granulation.

2. Agitation

The second stage involves agitating the wet mass using the high-speed rotor-stator system or chopper impeller. The agitation causes the particles to collide and shear against each other, leading to the formation of granules.

3. Drying

The final stage involves drying the granules to remove the moisture and improve their strength and stability. often the drying granules machine uses a fluid bed dryer to finish it.


High Shear Mixer Granulators Construction Material

Hywell Machinery is able to offer our GHL series lab high-shear mixer granulators with contact parts to be built in SS304, SS316L, Titanium, Duplex stainless steel, etc. For the control system of lab wet granulators, Hywell has choices on push button, PLC+HMI, and so on, and For the main electrical components of the high shear mixer granulator, it can choices the famous brand.


Conclusion

High shear mixer granulators are essential tools in pharmaceutical and chemical manufacturing processes. They offer numerous advantages, such as enhanced content uniformity, low shear force, easy scalability, flexibility, and GMP compliance. Choosing the right equipment, proper maintenance and cleaning, and addressing common challenges are critical for ensuring optimal performance and consistent product quality.


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